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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b5e21bae865ada87c95fd147644ed5338b7b6da9721b75e419558f90b22f45' 
  AND token = 'FK4S0vmwVGvb6/Kz84bsiNkzCxwq06AbFqXLhDtyxdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}