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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be3a316afaac658de2880e83c08f94633525b633a245e01c3ea52af621ad1006' 
  AND token = 'N4sIUTlySUB67MdHO+rrKDejN3zELuTLrK0xL2tkJkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}