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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2173cc4a325ccf270a619dda6e9db6a7f9d63caeb1bef959597af611e9df7f56' 
  AND token = '4TIvTkJTz6jVeFAA3FH+kFieEUN8fIJc2XYa+TbE3GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}