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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f770db1c8fd8b072045b0a0346543ec4003dcb4db246553407ae9f943fe6f252' 
  AND token = '2gfAlcSm5nMv1JXuypmcvjxiCU7Vgms5zUgmGdKMsQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}