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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75019b32bc5d6ddaf46164f76ee32917245bbc08fcd86c39298441560f9bf8fd' 
  AND token = 'uZ9Wxy+aN8KLT7Uu5PmwZAw3n1dcbbBbB0gxxX72Oiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}