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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2757c9937e9c75ecc65ed0d43fed5c9620abac2704ac2cb6e3b8498c852dcdb8' 
  AND token = 'HBiuqLx/7R+fGOdoeIZuStEOAAaYhNtTivs88tURmn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}