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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6922dc3af27c8593707f26f59bfc98f503b6cc20c35988b32f8602238fd4d081' 
  AND token = '/iAYi//4PpFC9Gt+kd0AO9UAowZi+GkPyZWQNocG+dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}