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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b8b451b2ea82b21677c1b65492fcf03d194788cc161081dbec2686ea700611' 
  AND token = 'MTfDZSboV4ADe4yS+BOyt1Gv2qXY7LHiBL+ALoIQ20E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}