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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294f77cec1dfbb5536346976f57e00e44a90d40cc2db19e778d5593c6ff8d844' 
  AND token = 'EGP4Z4+1LK0VvBtLIzRalrmkxe0YmcbWuy76RUHjIbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}