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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c4f44d68944b50771229032986cbb55515a478f7d4916f23c5277b58fd834e' 
  AND token = '5TsKybHf7Mh11+87XveFAzUokdlQYdWRDRKXsQaNio8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}