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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c8e2db438f286c849111ce4c49043af2cbe164b62b7247101c145dc135ce66' 
  AND token = 'LEQSBQuCSykHtlfmotrXcdMEDIOz5XZj1v8aUWLRhKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}