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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60316ccd923fb0fc2b89f700694855a82c9c377dc3a286f90788d4276fa0a8d5' 
  AND token = 'qiPdKO7P/TLV5mP7BjYOwrxtPkZeDr2UesV7EUk9JkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}