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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f638646248dcc98e1da9a3550470bb341130ada961d53f1c9d1512a44f47ed1d' 
  AND token = 'iVdOrN/6KutYTBaSrneXZbD0jb+WH7YOi4QvLJ+yphM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}