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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4c26bbd220459da5d2c9fbcd5963a052a5169289a81259d938267ad3fa3729' 
  AND token = 'CnEddbNBtgm0O+fs8jsws+G1S0EXt2dzMaZx3kDKYqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}