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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0d9b80cd858105ee21326c974e9842ea9de863b5c3caad2d81bdecbd95cdbd' 
  AND token = 'X34zyCWU9kl9cpG45Q5Rxi+/VZfNdFIr3VhgloTN0M8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}