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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c13747a4bcdb7e08a8633e4c3caaecce867da639c780c776150760ce283f9c7f' 
  AND token = 'YG3yRPd9T1MqvXJ6uEHBKchAI4+C+v5r3LIFVga2reE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}