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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2925cec4df746b83a78b74fcb9fe21ec94ef4918eb0ad1f5dc298ef695913c32' 
  AND token = 'LjY4BPPKIQ7UDbUnovbnHf3aKYg1QItR/gwe6IpohOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}