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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccceddbbec15d314473d732a8082d6fb81e746833715fb9ee0dcd11f1a3989a' 
  AND token = 'ba00GHxe4qO/0Tloi9v9Bx5/hljVmdL2uXYZMKtxCKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}