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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d0bd3741c8cbf70ab8276bcca08d83f1e164c5b84bd53bd1e6aa6c16b4edca' 
  AND token = 'dgKrlClY3ybeejkEoMG/Xz7LLtf9hbxI9oA3uI3oc5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}