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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8946185a532a130c6a51b07c0224572c8c44ba09f149a4418c63ca2b40402da0' 
  AND token = '1fYCrh6Oa/ubWPsLu8oeuxJt0qvV3bTYlsoSFymkhRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}