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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad03ae5cacd5e90c60f02fab48d597642cbccd077c3f64b319d03202dc0cfc79' 
  AND token = 'jONmjiCpzDew0ur+h610Y65f+LxrQ3T5sY5Fclx6OxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}