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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a19a7a3e33f50d382df41ffaaa1b609d88d86f6428bf8ae67ac1226ab74431' 
  AND token = 'sWFHWtSgW8ZIigdwlOqdNADSNPWD4BeaYaNYdQ2PSlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}