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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6286a57f02a1e2c2a479e37bd05254801eaf0c2f40d745dbe6da0e2cea7df9d2' 
  AND token = 'icMKSrPdkEiUSRsaRKft4CHogTBPB83rwooedwPELq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}