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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39547bb8d9749af640b74c2a1d447803d50e0900f6a528f01ebccfecf7a30449' 
  AND token = 'HxTCgdaqQ4TSZImw+/RRSb/WXSXN3DkkASBmboYh+qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}