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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d0dd1fd2e32a0d40fcda8f49b048feaad6847e7a480d6dd77960bee9af3af0' 
  AND token = 'Mc/XVgcP8hekuY53hOrn9rT9YXqRYuLK3lAtTQVOAg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}