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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c60a5bbd267b7076ee96e39df7b238ab7809f8501ee5da17cc8528c1e17288d' 
  AND token = 'EfbrhbfJyKlOytMT60BqYMFKMTLJVRESXbfmADHiJqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}