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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1074475e3afb514f075aa39cd354e12990591c824a6237668b683607465b378f' 
  AND token = 'cs0yv1/LVI+2zvtUHKaC51xcvSV0/MpdsaUTWar0X+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}