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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d483c2cc1276fd74bdff6ec9be9f35b393a41fd4e43b022d41f7478a4a12885' 
  AND token = 'QWcyfGeVGDm/aTy1zxQTzaa4HD5VJw+McdyL5ogC8rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}