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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401918d9a28935e3674cd12e1d4c04f71f26c5ecd474e6cb8de4ebab8d25677d' 
  AND token = 'G5mEfb0faMnqIcGXB+6EiC+bqQlgeh8qw4pZjrX9cws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}