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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48097f29a40ff92b4a9fe032b640dcc45422f740d66209427e8094a6e079338' 
  AND token = 'VWn8LAMzC9Mid9u116vQ/qRx7emZoL1RzyTGIfdek9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}