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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4996901d72d1c6f17016f189b776902259428ed1d8109e9f5e7ded0cadd949' 
  AND token = 'E2zuPHSxe5+TLOIWVTKS2RVFlSnfCm3euyBUoIrM1WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}