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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ed660931c53272e8511a7bdd029d6b6078a6f7d150744cc6b02316fb85613d' 
  AND token = 'XQQxgFN59CiBga1S9RPtqkwB/NiEnfLPHA49/3mWEWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}