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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288d87baaeefbf0657a65ae69009e23ab793fabf1bcdf2b25368316b5dbd7a15' 
  AND token = 'VZj98BnfW0jiccyjVDabY81fVCz3VK+LBT7ZKg/1dbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}