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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0ab5dff0927bed9fe5025a188675e8839eb7afc4350662208dbeb0ae27da51' 
  AND token = '8OjcvZVJTmD25bhThUs4odnVL+Y+BdAtByUELKBWFQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}