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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e21e5d1a635349ad8eaf87887a9fb5c057bc616d49be4a687e34b5b4f73754' 
  AND token = '1zNarEM11/V3tY5qGwh+GhfAje18nX+jE3/Z8Nu1tdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}