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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3da37328c49965f24883dc91c11481c69f68dc051bf8242d26c9abc67f36d5' 
  AND token = 'ecuPrdgaKAgLQs4bJAM9MTYtFCekSDp+2idKzXin/vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}