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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d735f615a2648df3ffbd66887fa8f4b97ee1caad9d0e1fc38e57512d398c25c' 
  AND token = '9aqVjFp3AI+J1ZIOyY1ftolfHEod0j/rMw9i0QufDLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}