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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc601ac50b7170f1b4252e8fcf4b7f99c62a14fe4e9720f4cc97f3c950c7e059' 
  AND token = 'VQ0nzkz8pU+kfHDhAfwkVzRxT+9q9dANeXqkQh3GPKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}