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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ef3f5af4060ded45ab05d271cfcaecb722b2333d4484313857b9ad40a31a4a' 
  AND token = '4D9sfnLI9qQkr7oHX+KZO8grmhBdXagntdIs8A7Cll4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}