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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '402205b6696974826f86921d077454e5f68b87ce20aeb1b1d3e5d548e8252303' 
  AND token = 'yZIchSsTYbfTq+Dn2OSkMuGDWycoMxqgoTU6bSoPDhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}