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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0d35d0c849f8b2556c3f2fe56ca958d189368f249d3658eeb08964d4b6452a8' 
  AND token = 'S5rgNBOWznQbukCij3849tphzeXte5jerok+ZQ37ebY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}