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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea48d1ebfd328a89c541dd6e162f76b0906f9d878125372537c14cb533a5c0a' 
  AND token = 'kG/nDQQF2k4LFfpHuxPJIDyDI2tM48L/HsYPr+rdJg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}