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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd852da99e3b2cd2cfb892c81f9b0482d27e3c08a695cb2bcd97f39759a9f0626' 
  AND token = 'O9hOgEkQUKQKodDWEMMBBP+mnWk4U8lZuJ3LnGHm8qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}