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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6d8c1dc2d8b90e211fb25e57fdc59700f63f5cbd030c41a6b24bbee8ca3847' 
  AND token = 'oikoP9CWgZRSmYTuU0tSVn36UWbF4yvZGoPx4VPAWkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}