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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4058805b63c3a90a261af345b5b4fe8e055e87f76070c002e99314840e2d0d2' 
  AND token = 'J01GBGsE97ngTkPG7w/mM0m7MtOEazM+grvdOz9tV7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}