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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c8fcfb357f9aa7817844c8ad7725c10aee846bfc67cbec650d71321d2bc3ee' 
  AND token = 'fQZi/Q8Rg4XFTuGCSOm0FBFIGUAB8uso2aZe6rWpBQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}