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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e6076564c766ae247d52fd282e5bd43986cc988d5d2e3d6e2a5e61a91eab71' 
  AND token = 'S1GNRnOwZD+wfeIDlFAwzmayC2S2mVEJcBh6PUuw50o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}