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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5774701ef6345b771fcce8797ef276cbf7c02a6242ea1b9574bec98c3fce12' 
  AND token = '2LxjcGtqW1ErT0QYGfG3R+CDTAPwJiVRqa3vXF28Pes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}