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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686a123c382c1755c7fbc1a2e1d8eff054b9b1beec103730f603d2f2ee8ce4f5' 
  AND token = 'HwHQbrWQG/i9YPMnh51K4mULSRkA9ebSmP2mpKMvACQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}