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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c9e33ea441f5c091028fc252fe74dccdb663a87078e0c0f6470c2dd6693f03' 
  AND token = '5Jn4K9C7dwyFtSquqMvKCkwlnKm+L4PtO4cEzcQ8rUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}